Project information
CIISB - Czech Infrastructure for Integrative Structural Biology
(CIISB)
- Project Identification
- LM2023042
- Project Period
- 1/2023 - 12/2026
- Investor / Pogramme / Project type
-
Ministry of Education, Youth and Sports of the CR
- Large Infrastructures for Research, Development and Innovation
- MU Faculty or unit
- Central European Institute of Technology
- Project Website
- https://www.ciisb.org/
- Cooperating Organization
-
Institute of Biotechnology CAS
- Responsible person Ing. Jan Dohnálek, PhD.
The Czech Infrastructure for Integrative Structural Biology (CIISB) is a distributed national infrastructure, which consists of two nodes, one represented by CEITEC (Central European Institute of Technology, Brno) and second by BIOCEV (Biotechnology and Biomedicine Centre of the Academy of Sciences and Charles University, Vestec near Prague). CIISB offers access to 10 core facilities; five of them are part of the Centre of Structural Biology and one of the Mendel Centre of Genomics and Proteomics of Plants of CEITEC Masaryk University and four of the Centre of Molecular Structure of the Institute of Biotechnology AS CR in the BIOCEV Centre.
All CIISB core facilities are in the full operational phase. Projects as OP RDI (Start-up) supported the construction phase, and the built capacities were made available by both CIISB nodes in the form of Open Access to internal and external users. In its construction phase, CIISB (2011-2015) was the Associated National Center of the pan-European research infrastructure INSTRUCT. In 2016, following the completion, putting into operation, and subsequent international evaluation, CIISB became a fully-fledged Instruct-CZ Centre for this distributed infrastructure.
Sustainable Development Goals
Masaryk University is committed to the UN Sustainable Development Goals, which aim to improve the conditions and quality of life on our planet by 2030.
Publications
Total number of publications: 152
2026
-
From patient to tumor organoid: Culture protocol choice controls glioblastoma tumor architecture and identity
BRAIN PATHOLOGY, year: 2026, DOI
-
Genomic and taxonomic characterization of strain CCM 2573: Uncovering unique genetic features and description of Macrococcus caseolyticus subsp. lactis subsp. nov.
FOLIA MICROBIOLOGICA, year: 2026, DOI
-
Label matters: comparing gold nanoparticles and nanoshells with upconversion nanoparticles for quantitative lateral flow immunoassays
Microchimica Acta, year: 2026, volume: 193, edition: 4, DOI
-
Lost cells, retained structure: proteomic mapping of decellularized lung matrisome across species
MATERIALS & DESIGN, year: 2026, volume: 270, edition: October 2026, DOI
-
Mass Spectrometry-Based Analysis of Serum N-glycan Biomarkers for Rapid Lung Cancer Detection
JOURNAL OF ANALYSIS AND TESTING, year: 2026, DOI
-
Microgliosis and aberrant interferon response in Adar Mavs brain are rescued by PKR removal
BRAIN, year: 2026, volume: 149, edition: 2, DOI
-
Molecular trick to reverse SN2 step in a haloalkane dehalogenase
Chem Catalysis, year: 2026, volume: 6, edition: 5, DOI
-
Plošný substrát pro elektrochemický jednokanálový senzor chytré náplasti
Year: 2026
-
PRICKLE3 protects VANGL proteins from CK1-mediated phosphorylation and RNF43-mediated degradation
Communications Biology, year: 2026, volume: 9, edition: 1, DOI
-
Proteomic Analysis of Histone Sequence Variants and Post-translationally Modified Forms
, edition: Vyd. 1510, year: 2026, number of pages: 27 s., DOI