Informace o projektu
CIISB - Česká infrastruktura pro integrativní strukturní biologii
(CIISB)
- Kód projektu
- LM2023042
- Období řešení
- 1/2023 - 12/2026
- Investor / Programový rámec / typ projektu
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Ministerstvo školství, mládeže a tělovýchovy ČR
- Velké infrastruktury pro výzkum, vývoj a inovace
- Fakulta / Pracoviště MU
- Středoevropský technologický institut
- Spolupracující organizace
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Biotechnologický ústav AV ČR, v.v.i.
- Odpovědná osoba Ing. Jan Dohnálek, PhD.
The Czech Infrastructure for Integrative Structural Biology (CIISB) is a distributed national infrastructure, which consists of two nodes, one represented by CEITEC (Central European Institute of Technology, Brno) and second by BIOCEV (Biotechnology and Biomedicine Centre of the Academy of Sciences and Charles University, Vestec near Prague). CIISB offers access to 10 core facilities; five of them are part of the Centre of Structural Biology and one of the Mendel Centre of Genomics and Proteomics of Plants of CEITEC Masaryk University and four of the Centre of Molecular Structure of the Institute of Biotechnology AS CR in the BIOCEV Centre.
All CIISB core facilities are in the full operational phase. Projects as OP RDI (Start-up) supported the construction phase, and the built capacities were made available by both CIISB nodes in the form of Open Access to internal and external users. In its construction phase, CIISB (2011-2015) was the Associated National Center of the pan-European research infrastructure INSTRUCT. In 2016, following the completion, putting into operation, and subsequent international evaluation, CIISB became a fully-fledged Instruct-CZ Centre for this distributed infrastructure.
Cíle udržitelného rozvoje
Masarykova univerzita se hlásí k cílům udržitelného rozvoje OSN, jejichž záměrem je do roku 2030 zlepšit podmínky a kvalitu života na naší planetě.
Publikace
Počet publikací: 121
2025
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Bispecific Thio-linked Disaccharides as Inhibitors of Pseudomonas aeruginosa Lectins LecA (PA-IL) and LecB (PA-IIL): Dual-Targeting Strategy
Chemistry – A European Journal, rok: 2025, ročník: 31, vydání: 5, DOI
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Characterization of Heterorhabditis bacteriophora response to insect-derived and non-biological stimuli: Insights into nematode recovery and released proteins
Pesticide Biochemistry and Physiology, rok: 2025, ročník: 208, vydání: March, DOI
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Characterization of multiple binding sites on microtubule associated protein 2c recognized by dimeric and monomeric 14-3-3ζ
The FEBS Journal, rok: 2025, DOI
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Non-hydrolytic sol-gel synthesis of amine-functionalized silica: Template- and catalyst-free preparation of mesoporous catalysts for CO<sub>2</sub> valorization
Microporous and Mesoporous Materials, rok: 2025, ročník: 381, vydání: Jan, DOI
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Novel archaeal ribosome dimerization factor facilitating unique 30S-30S dimerization
Nucleic acids research, rok: 2025, ročník: 53, vydání: 2, DOI
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Piezoelectric biosensor with dissipation monitoring enables the analysis of bacterial lytic agent activity
Scientific Reports, rok: 2025, ročník: 15, vydání: January, DOI
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Pseudomonas rossensis sp. nov., a novel psychrotolerant species produces antimicrobial agents targeting resistant clinical isolates of Pseudomonas aeruginosa
Current Research in Microbial Sciences, rok: 2025, ročník: 8, vydání: 2025, DOI
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Specific inhibition of fibroblast growth factor receptor 1 signaling by a DNA aptamer
MOLECULAR THERAPY-NUCLEIC ACIDS, rok: 2025, ročník: 36, vydání: 1, DOI
2024
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37th Central European NMR Meeting, NMR Valtice 2024
Rok: 2024, druh: Uspořádání konference
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A hybrid DDA/DIA-PASEF based assay library for a deep proteotyping of triple-negative breast cancer
Scientific Data, rok: 2024, ročník: 11, vydání: 1, DOI