Project information
Mechanobiology in prostate cancer: Tumour aggressiveness associated with cell stiffness
- Project Identification
- MUNI/IGA/0954/2021
- Project Period
- 1/2022 - 12/2022
- Investor / Pogramme / Project type
-
Masaryk University
- Internal grant agency MU
- MU Faculty or unit
- Faculty of Medicine
Specific mechanical features of cancer cells are essential for tumour progression and could provide interesting targets for treatment. This project aims on describing mechanobiological properties of aggressive and non-aggressive prostatic cancer cells using advanced methods, such as Quantitative phase imaging, Atomic force microscopy and Confocal microscopy. Combination of these methods should bring new insight on the mechanobiology of prostate cancer progression.
Publications
Total number of publications: 3
2023
-
Magnetically Driven Self-Degrading Zinc-Containing Cystine Microrobots for Treatment of Prostate Cancer
SMALL, year: 2023, volume: 19, edition: 17, DOI
2022
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Cancer cell viscoelasticity measurement by quantitative phase and flow stress induction
Biophysical Journal, year: 2022, volume: 121, edition: 9, DOI
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Pentamethinium salts suppress key metastatic processes by regulating mitochondrial function and inhibiting dihydroorotate dehydrogenase respiration
Biomedicine & Pharmacotherapy, year: 2022, volume: 154, edition: October 2022, DOI