Loschmidt Laboratories of Protein Engineering

Articles

• Molecular trick to reverse SN2 step in a haloalkane dehalogenase

  TOUL Martin MARQUES Sérgio Manuel GAO Tadeja BERNHARDOVÁ Hana VÁVRA Ondřej NOVÁKOVÁ Veronika DAMBORSKÝ Jiří BEDNÁŘ David PROKOP Zbyněk MAREK Martin

  Peer-reviewed scientific article

  Chem Catalysis, year: 2026, volume: 6, edition: 5, DOI

• Naringenin as a dual-target modulator of RAGE-NF-κB signaling and Aβ fibrillization in Alzheimer's disease: integrated computational and experimental analyses

  BHOGAL Inderjeet FRYDRYCH Ivo MODI Ajay PANKAJ Vaishali KUMAR Akhil KHAIRNAR Amit Suresh DAS Viswanath ROY Sudeep

  Peer-reviewed scientific article

  FRONTIERS IN PHARMACOLOGY, year: 2026, volume: 17, edition: August 2026, DOI

• Rapid screening of staphylokinase protein variants using an unpurified cell-free expression system

  TOMKOVA Maria HOVANOVA Veronika DAMBORSKÝ Jiří SEDLAK Erik

  Peer-reviewed scientific article

  FEBS Open Bio, year: 2026, volume: 16, edition: 8, DOI

• Regioselective Sesquiterpene Hydroxylation Directed by Tunnel Remodeling in Rieske Oxygenases

  BERGER Jonathan B. MARQUES Sérgio Manuel WISSNER Julian L. SCHELLE Jona T. BEEKWILDER Jules DAMBORSKÝ Jiří HAUER Bernhard

  Peer-reviewed scientific article

  JACS Au, year: 2026, volume: 6, edition: 2, DOI

• Structural insights into the evolution of alpha/beta-hydrolase fold luciferases

  MAJEROVÁ Marika HORÁČKOVÁ Jana SEDLÁČKOVÁ Karolina ŠULOVÁ Marie KOVÁŘ David DAMBORSKÝ Jiří PROKOP Zbyněk BEDNÁŘ David MAREK Martin

  Peer-reviewed scientific article

  International journal of biological macromolecules, year: 2026, volume: 361, edition: May 2026, DOI

• Taurine inhibits apolipoprotein E4 aggregation

  LEGRAND Anthony Thomas P AMRUZ ČERNÁ Kateřina MARQUES Sérgio Manuel VERMA Naina KOPKO Jakub VÁŇOVÁ Tereza SUBRAMANIAN Madhumalar KURSIT Aliaksandra BENDL Jaroslav HENEK Tomáš VAŇÁČEK Pavel KUCERA Josef PLANAS IGLESIAS Joan SEDMÍK Jiří POSPÍŠILOVÁ Veronika KOUBA Petr VAŠKOVÁ Aneta NEZVEDOVÁ Markéta SEDLÁŘ Jiri DAMBORSKÝ Jiří PROKOP Zbyněk

  Peer-reviewed scientific article

  BIOMEDICINE & PHARMACOTHERAPY, year: 2026, volume: 199, edition: 119395, DOI

• The effect of salidroside, an active component of Rhodiola rosea, on the metabolic activity of rat and human cytochromes P450 in preclinical studies

  KLÁSKOVÁ Eva JUŘICA Jan DANEK Przemyslaw Jan MLČŮCHOVÁ Natálie EYRILMEZ Saltuk Mustafa BOŘILOVÁ LINHARTOVÁ Petra BEDNÁŘ David KAMARAJ Rajamanikkam DANIEL Wladyslawa Anna ZENDULKA Ondřej

  Peer-reviewed scientific article

  Pharmacological Reports, year: 2026, volume: 78, edition: 3, DOI

• Thrombolytic proteins profiling: High-throughput activity, selectivity, and resistance assays

  TOUL Martin STRUNGA Alan DAMBORSKÝ Jiří PROKOP Zbyněk

  Peer-reviewed scientific article

  FEBS Open Bio, year: 2026, volume: 16, edition: 2, DOI

• Tryptophanase Mining and Characterization toward the Biological Production of Indole Derivatives

  DE BOER Ruben M. HARDING-LARSEN David MAZURENKO Stanislav WELNER Ditte Hededam

  Peer-reviewed scientific article

  ACS Omega, year: 2026, volume: 11, edition: 9, DOI

Patents

• 热稳定性FGF2多肽、其用途

  DVOŘÁK Petr KREJČÍ Pavel BÁLEK Lukáš EISELLEOVÁ Lívia KONEČNÁ Žaneta DVOŘÁK Pavel BEDNÁŘ David BREZOVSKÝ Jan ŠEBESTOVÁ Eva CHALOUPKOVÁ Radka ŠTĚPÁNKOVÁ Veronika VAŇÁČEK Pavel PROKOP Zbyněk DAMBORSKÝ Jiří BOSÁKOVÁ Michaela

  Patent

  Publisher: China National Intellectual Property Administration, state: China, patent's number: CN108779158, year: 2026