Theranostics (therapy and diagnostics) represent a new basis for a modern approach to treatment. Stroke is a significant burden on the modern society nowadays (not only after the SARS-CoV-2 pandemic). This project aims to study the pharmacokinetic properties of polyiodinated biodegradable nanoparticles (IoNPs) based on theranostics using a novel combination of in vivo and ex vivo imaging methods. On this basis, it further aims to develop (using a future image database developed by us) the detection of ischemic stroke age on tissue sections in a combination of machine learning methods. The results of this project will have a significant impact on society as a whole, ranging from the possibility of applying IoNPs in clinical practice, to the necessary choice of individual patient treatment to save their life, to the reduced economic burden associated with long-term treatment, rehabilitation and loss of productivity.

Sustainable Development Goals

Masaryk University is committed to the UN Sustainable Development Goals, which aim to improve the conditions and quality of life on our planet by 2030.