Project information
New Strategies For The Early Diagnosis, Risk Stratification and Co-management of Familial Hypercholesterolemia
(FH-EARLY)
- Project Identification
- 101155885
- Project Period
- 1/2025 - 12/2028
- Investor / Pogramme / Project type
-
European Union
- Horizon Europe
- Cluster 1 - Health
- MU Faculty or unit
- Faculty of Medicine
- Cooperating Organization
-
University of Helsinki
Hacettepe University
Université Paris 1 - Sorbonne
Leiden University Medical Center
Ege University
Associaçao para Investigaçao e Desenvolvimento da Faculdade de Medicina
- Responsible person Fausto J. PINTO
Stichting FH Europe Foundation
Instituto Nacional de Saúde Dr. Ricardo Jorge
Saint Joseph University
Moncyte
Center for Innovation in Medicine
- Responsible person Bianca Cucos
Stichting Nederlandse Wetenschappelijk Onderzoek Instituten
FH-EARLY will enable new strategies for earlier diagnosis and co-management of familial hypercholesterolemia . The project works with FH families with inherited cholesterol: parents, children (7-12), teenagers (13-18) and carers to co-create and test solutions. The three interrelated solutions are: a new chip array, enabling easier, cheaper and earlier diagnosis; a signature biomarker assay that provides unique risk stratification and personalized treatment strategies to FH and general population; an integrative precision health profiling (iPHP) tool using explainable AI to model well-defined data flows from multi-modal data in several patient cohorts across Europe. FH-EARLY will help prevent premature coronary heart disease, not only for FH patients, but also within the general population: with potential to generate considerable economic and social benefits.
Sustainable Development Goals
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