Project information
Junior research group: Choroid Plexus in Diseases
- Project Identification
- MUNI/11/JRG/1143/2023
- Project Period
- 10/2023 - 9/2026
- Investor / Pogramme / Project type
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Masaryk University
- Junior Research Group
- MU Faculty or unit
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Faculty of Medicine
- Alemeh Zamani, Ph.D.
- prof. Mgr. Václav Brázda, Ph.D.
- Malahatosadat Dianat, Ph.D., Ph.D
- Parisa EmamiAref
- Karolína Jeřábková
- Andrea Joukal
- Mgr. Petra Orviská
- Nir Yavin
- Alemeh Zamani, Ph.D.
- doc. Ahad Zareravasan, PhD
My research focuses on the role of the choroid plexus in pathology, which is an essential structure located in the brain ventricles responsible for producing cerebrospinal fluid and forming the blood-cerebrospinal fluid barrier. Dysfunction of the choroid plexus has been linked to various neurological disorders, including neuroinflammation and neurodegeneration. Despite its clinical importance, the choroid plexus remains understudied, prompting us to expand our knowledge of its pathophysiological mechanisms, particularly in Alzheimer's disease and chemotherapy-induced neuropathy, two devastating conditions with no known cure. With over four years of experience studying the choroid plexus, I seek to uncover novel insights into these conditions and contribute to the advancement of the field.
Sustainable Development Goals
Masaryk University is committed to the UN Sustainable Development Goals, which aim to improve the conditions and quality of life on our planet by 2030.
Publications
Total number of publications: 6
2024
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Chemotherapy alters the Kolmer cell of the choroid plexus
Year: 2024, type: Conference abstract
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Investigate the Role of Choroid Plexus in Alzheimer’s Disease
Year: 2024, type: Appeared in Conference without Proceedings
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Neuropathic pain and immunoreactive dynamics investigating the influence of paclitaxel in brain ventricles
Year: 2024, type: Appeared in Conference without Proceedings
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Paclitaxel triggers molecular and cellular changes in the choroid plexus
Frontiers in pain research, year: 2024, DOI
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Tau phosphorylation and neuroinflammatory response to Aβ in choroid plexus cells
Year: 2024, type: Appeared in Conference without Proceedings
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The reaction of choroid plexus to chemotherapy
Year: 2024, type: Appeared in Conference without Proceedings