Project information
Prenatal treatment of achondroplasia

Information

This project doesn't include Faculty of Science. It includes Faculty of Medicine. Official project website can be found on muni.cz.

Project Identification

NU23-10-00550

Project Period

5/2023 - 12/2026

Investor / Pogramme / Project type

Ministry of Health of the CR

Ministry of Health Research Programme 2020 - 2026
Subprogram 1 - standard

MU Faculty or unit

Faculty of Medicine

Cooperating Organization

Institute of Molecular Genetics of the ASCR, v. v. i.

Responsible person Mgr. Jan Procházka, Ph.D.

Viz návrh projektu.

Sustainable Development Goals

Masaryk University is committed to the UN Sustainable Development Goals, which aim to improve the conditions and quality of life on our planet by 2030.

Publications

Total number of publications: 4

2025

Endoplasmic reticulum stress disrupts signaling via altered processing of transmembrane receptors

BOSÁKOVÁ Michaela POOVAKULATHU ABRAHAM Sara WACHTELL Davis ZIEBA Jennifer T KOT Alexander NITĂ Alexandru CZYREK Aleksandra Anna KOUDELKA Adolf URSACHI Vlad-Constantin FEKETOVÁ Zuzana RICO-LLANOS Gustavo SVOZILOVÁ Kateřina KOCEROVÁ Petra FAFÍLEK Bohumil GREGOR Tomáš KOTAŠKOVÁ Jana DURAN Ivan VAŇHARA Petr DOUBEK Michael MAYER Jiří SOUČEK Karel KRAKOW Deborah KREJČÍ Pavel

Article in Periodical

Cell Communication and Signaling, year: 2025, volume: 23, edition: 1, DOI
Increased thermal stability of FGF10 leads to ectopic signaling during development

CZYREK Aleksandra Anna BARAN Karolina HRUBÁ Eva HORACKOVA Aneta BOSÁKOVÁ Veronika CHUDZIAN Julia FAFÍLEK Bohumil LASKOVA Veronika STEPANKOVA Veronika BEDNÁŘ David KARL Kelly KASPAREK Petr BOSÁKOVÁ Michaela KILLINGER Michal SZOTKOWSKA Tereza PROCHAZKA Jan ZIEBA Jennifer T RICO LLANOS Gustavo FRIČ Jan HADZIC Stefan LOKU Edma WUJAK Magdalena SVOZILOVÁ Kateřina STROBLOVÁ Michaela SEDLACEK Radislav HRISTOVA Kalina KRAKOW Deborah KUBOVCIAK Jan DELATTRE Mathys BARTOSZEWSKI Rafal BUCHTOVÁ Marcela KROWARSCH Daniel CHALOUPKOVÁ Radka ZAKRZEWSKA Malgorzata KREJČÍ Pavel

Article in Periodical

Cellular and molecular life sciences, year: 2025, volume: 82, edition: 1, DOI
Specific inhibition of fibroblast growth factor receptor 1 signaling by a DNA aptamer

ZLÍNSKÁ Vladimíra FEKETOVÁ Zuzana CZYREK Aleksandra Anna CHUDZIAN Julia ZIVKOVIC Martina Lenarcic URSACHI Vlad-Constantin DUDEJA Pooja FAFÍLEK Bohumil RYNEŠ Jan RICO LLANOS Gustavo KOUDELKA Adolf ROY Tanaya BIADUN Martyna RAŠKOVÁ Vendula SVOZILOVÁ Kateřina STROBLOVÁ Michaela KRZYSCIK Mateusz HRISTOVA Kalina KROWARSCH Daniel TRANTÍRKOVÁ Silvie ZAKRZEWSKA Malgorzata TRANTÍREK Lukáš KREJČÍ Pavel

Article in Periodical

MOLECULAR THERAPY-NUCLEIC ACIDS, year: 2025, volume: 36, edition: 1, DOI

2024

Achondroplasia: aligning mouse model with human clinical studies shows crucial importance of immediate postnatal start of the therapy

RICO LLANOS Gustavo SPOUTIL Frantisek BLAHOVÁ Eva KOUDELKA Adolf PROCHAZKOVA Michaela CZYREK Aleksandra Anna FAFÍLEK Bohumil PROCHAZKA Jan GONZÁLEZ LÓPEZ Marcos KŘIVÁNEK Jan SEDLACEK Radislav KRAKOW Deborah NONAKA Yosuke NAKAMURA Yoshikazu KREJČÍ Pavel

Article in Periodical

Journal of bone and mineral research, year: 2024, volume: 39, edition: 12, DOI