Project information
National Institute of Virology and Bacteriology
(NIVB)
- Project Identification
- LX22NPO5103
- Project Period
- 6/2022 - 12/2025
- Investor / Pogramme / Project type
-
Ministry of Education, Youth and Sports of the CR
- national recovery plan
- 5.1 EXCELES
- MU Faculty or unit
-
Central European Institute of Technology
- prof. RNDr. Robert Vácha, PhD.
- Mgr. Gabriel Demo, Ph.D.
- Mgr. Martina Drabinová
- Francesco Luca Falginella, Ph.D.
- Ing. Tibor Füzik, Ph.D.
- Mgr. Mária Gondová
- Ing. et Ing. Miroslav Haman
- Mgr. Adelheid Hanáčková
- Ing. Ondřej Kroutil, Ph.D.
- Timothée Emmanuel Jonath Rivel, Ph.D.
- Mgr. Jana Salamonová
- prof. RNDr. Robert Vácha, PhD.
- Other MU Faculty/Unit
- Faculty of Medicine
- Other MU Faculty/Unit
-
Faculty of Science
- prof. RNDr. Roman Pantůček, Ph.D.
- Mgr. Tibor Botka, Ph.D.
- Lenka Buňatická
- prof. RNDr. Jiří Doškař, CSc.
- Mgr. Adéla Finstrlová, Ph.D.
- Mgr. Jiřina Havránková
- Mgr. Vojtěch Kovařovic, Ph.D.
- Mgr. Lucie Kuntová, Ph.D.
- Mgr. Ivana Mašlaňová, Ph.D.
- Mgr. Michal Zeman, Ph.D.
- Cooperating Organization
-
Institute of Microbiology of the ASCR, v. v. i.
Institute of Molecular Genetics of the ASCR, v. v. i.
Institute of Organic Chemistry and Biochemistry of the ASCR, v. v. i.
- Responsible person RNDr. PhDr. Zdeněk Hostomský, CSc.
Palacký University, Olomouc
Prague Institute of Chemical Technology
Biological Centre of the ASCR, v. v. i.
Basic and oriented or clinical research on viruses and pathogenic bacteria is essential to understand the processes by which they cause disease, how they escape the immune system and how they can resist treatment. Therefore, research activities at the National Institute of Virology and Bacteriology will focus on characterizing pathogens causing existing and emerging infectious diseases, describing virus and bacteria interactions with the host, understanding the molecular mechanisms of pathogenesis, and developing antiviral and antibacterial agents and vaccines. Individual research groups will work on viruses and bacteria causing diseases with significant health and economic impact, including HIV-1, influenza, tick-borne encephalitis, hepatitis B, SARS-CoV-2, enteroviruses, and the bacteria B. pertussis, S. aureus, and T. pallidum. By working with pathogens that are relevant to current clinical practice, the research groups will have the expertise and equipment for the ongoing study of new pathogens that could become prevalent in the human population in the future.
Sustainable Development Goals
Masaryk University is committed to the UN Sustainable Development Goals, which aim to improve the conditions and quality of life on our planet by 2030.
Publications
Total number of publications: 115
2024
-
A reusable QCM biosensor with stable antifouling nano-coating for on-site reagent-free rapid detection of E. coli O157:H7 in food products
Food Control, year: 2024, volume: 165, edition: November 2024, DOI
-
Amphipathic Helices Can Sense Both Positive and Negative Curvatures of Lipid Membranes
Journal of physical chemistry letters, year: 2024, volume: 15, edition: 1, DOI
-
Autoantibodies neutralizing type I IFNs underlie severe tick-borne encephalitis in ∼10% of patients
JOURNAL OF EXPERIMENTAL MEDICINE, year: 2024, volume: 221, edition: 10, DOI
-
Brno loanvirus (BRNV) in bats inhabiting the urban area of Brno, Czech Republic
Infection, Genetics and Evolution, year: 2024, volume: 121, edition: July, DOI
-
Clinical and genomic diversity of Treponema pallidum subspecies pallidum to inform vaccine research: an international, molecular epidemiology study
The Lancet Microbe, year: 2024, volume: 5, edition: 9, DOI
-
Coinfection of a yaws patient with two closely related Treponema pallidum subsp. pertenue strains: A rare event with potential evolutionary implications
Acta Tropica, year: 2024, volume: 256, edition: August 2024, DOI
-
Computational Design of Pore-Forming Peptides with Potent Antimicrobial and Anticancer Activities
Journal of Medicinal Chemistry, year: 2024, volume: 67, edition: 16, DOI
-
Corynebacterium mendelii sp. nov., a novel bacterium isolated from Adélie penguin oral cavity
International Journal of Systematic and Evolutionary Microbiology, year: 2024, volume: 74, edition: 1, DOI
-
CRISPR-Cas10 Engineering of Staphylococcus aureus bacteriophages for biosensing applications
Year: 2024, type: Conference abstract
-
Distinct 30S subunit dimerization architecture facilitated by a novel ribosome dimerization factor in archaea
Year: 2024, type: Conference abstract