Project information
DIANA panel for testing of selectivity of inhibitors of clinically relevant protein kinases and its application in the drug discovery market. Preclinical development of new inhibitors of CDK11 - key enzyme for growth of cancer cells.

Project Identification

FW03010138

Project Period

1/2021 - 12/2024

Investor / Pogramme / Project type

Technology Agency of the Czech Republic

TREND
Subprograms 1 Technology leaders

MU Faculty or unit

Central European Institute of Technology

Mgr. Dalibor Blažek, Ph.D.

Other MU Faculty/Unit

Faculty of Science

doc. Mgr. Kamil Paruch, Ph.D.

Cooperating Organization

DIANA Biotechnologies, s.r.o.

Responsible person Mgr. Václav Navrátil, Ph.D.

Projekt má dva hlavní cíle:
1) Vyvinout metodu založenou na technologii DIANA pro měření afinity a selektivity inhibitorů CDK a dalších klinicky relevantních kináz.
2) Nalézt nové selektivní inhibitory CDK11 a provést jejich preklinický vývoj s ohledem na jejich potenciál pro léčbu onkologických indikací.

Sustainable Development Goals

Masaryk University is committed to the UN Sustainable Development Goals, which aim to improve the conditions and quality of life on our planet by 2030.

Project informationDIANA panel for testing of selectivity of inhibitors of clinically relevant protein kinases and its application in the drug discovery market. Preclinical development of new inhibitors of CDK11 - key enzyme for growth of cancer cells.

Sustainable Development Goals

Project information
DIANA panel for testing of selectivity of inhibitors of clinically relevant protein kinases and its application in the drug discovery market. Preclinical development of new inhibitors of CDK11 - key enzyme for growth of cancer cells.