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Project information
Biomolecular Center

Project Identification
LN00A016
Project Period
7/2000 - 12/2004
Investor / Pogramme / Project type
Ministry of Education, Youth and Sports of the CR
  • Research Centres
MU Faculty or unit
Faculty of Science
  • prof. RNDr. Jaroslav Koča, DrSc.
Keywords
Biomolecules, protein, oligonucleotides, NMR spectroscopy, computer simulations and modeling, protein engineering, DNA vaccines, bacteria "quorum systems"
Cooperating Organization
Institute of Biophysics
  • Responsible person prof. RNDr. Jiří Šponer, DrSc.
Veterinary Research Institurte
  • Responsible person doc. RNDr. Ivan Rychlík, Ph.D.

Biomolecular center is designed as an expert laboratory for studiyng the structure and properties of biologically relevant molecules and biopolymers, with main emphasis on proteins and nucleic acid fragments. On the horizontal level the Center will havea strong background in methods for studiing the biomolecules on the atomic level using NMR spectroscopy, molecular modeling and X-ray crystallography with appropriate support of biochemistry and molecular biology. The Center will be able to studythe biomolecular systems in the vertical direction starting with the atomic structure, through their in vitro properties to their function in living cells. From the very beginning, the Center will activelly participate in Ph.D programs (already now 14PhD. students). In the final stage, 25 core scientist will be employed in the Center with a significant support from postdoctoral fellows and PhD. students (2/3 of all coworkers). The group is involved in a large number of international projects.

Publications

Total number of publications: 127

2005

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