Project information
MEDGENET - Medical genomics and epigenomics network
(MEDGENET)
- Project Identification
- 692298
- Project Period
- 1/2016 - 12/2018
- Investor / Pogramme / Project type
-
European Union
- Horizon 2020
- Spreading excellence and widening participation
- MU Faculty or unit
- Central European Institute of Technology
- Cooperating Organization
-
European Molecular Biology Laboratory
Uppsala universitet
Centre for Research and Technology Hellas
The main goal of MEDGENET consortium is to use synergies and existing expertise in EU leading institutions such as EMBL, Uppsala University and CERTH to reinforce the productivity and competitiveness of the CEITEC in the field of medical genomics and epigenomics. We propose clear strategy based on combination of unique complementary skills present in partner institutions that will transform CEITEC into a key leader in the field. ERA Chair who recently joint CEITEC already initiated the transformational change of the institute and TWINNING framework will further support sharing her international contacts with other CEITEC researchers. MEDGENET aims to create well-educated taskforce of biomedical researchers, who will notably contribute to the development of new genomics and bioinformatics tools and their application in clinical practice. Proposed project will enable to establish the best practices for performing innovative and high-quality biomedical research and to strengthen CEITEC´s competence to translate the research results into high value-added clinical applications. Stimulation of knowledge exchange, implementation of cutting edge technologies and mastery of modern genomics and bioinformatics methodologies will have a direct impact on the overall research and innovation potential of CEITEC and will increase its visibility in the international scientific community.
Publications
Total number of publications: 53
2020
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Luminescent Sensor Based on Ln(III) Ternary Complexes for NAD(P)H Detection
Molecules, year: 2020, volume: 25, edition: 18, DOI
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Nuclear inclusions of pathogenic ataxin-1 induce oxidative stress and perturb the protein synthesis machinery
Redox Biology, year: 2020, volume: 32, edition: MAY 2020, DOI
2019
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Different time-dependent changes of risk for evolution in chronic lymphocytic leukemia with mutated or unmutated antigen B cell receptors
Leukemia, year: 2019, volume: 33, edition: 7, DOI
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Disease-biased and shared characteristics of the immunoglobulin gene repertoires in marginal zone B cell lymphoproliferations
JOURNAL OF PATHOLOGY, year: 2019, volume: 247, edition: 4, DOI
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Inhibition of miRNA-129-2-3p increases risk of seizure induction in developing brain
Year: 2019, type: Conference abstract
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Integrated epigenomic and transcriptomic analysis reveals TP63 as a novel player in clinically aggressive chronic lymphocytic leukemia
International journal of cancer, year: 2019, volume: 144, edition: 11, DOI
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MicroRNA miR-34a downregulates FOXP1 during DNA damage response to limit BCR signalling in chronic lymphocytic leukaemia B cells
Leukemia, year: 2019, volume: 33, edition: 2, DOI
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Tailored approaches grounded on immunogenetic features for refined prognostication in chronic lymphocytic leukemia
haematologica, year: 2019, volume: 104, edition: 2, DOI
2018
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A new deep intronic mutation caused aberrant splicing in a family diagnosed with hereditary angioedema
Year: 2018, type:
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Analýza rozsáhlých přestaveb genomu u chronické lymfocytární leukémie
Year: 2018, type: Conference abstract