Loschmidt Laboratories

Articles

• Aicardi-Goutieres Syndrome Type 6: Case Report and Structural Prediction Supporting a Dominant-Negative Effect of the ADAR1 c.3019G>A Variant

  TURAN Kateřina POKORNÁ Petra ŘÍHOVÁ Kamila KUBÁTOVÁ Jana KOŽELKOVÁ Kateřina HLOUŠKOVÁ Eliška DANHOFER Pavlína JABANDŽIEV Petr DAMBORSKÝ Jiří DEMLOVÁ Regina SLABÝ Ondřej SLABÁ Kateřina

  Peer-reviewed scientific article

  CLINICAL CASE REPORTS, year: 2026, volume: 14, edition: 4, DOI

• Concentration-dependent dimerization of staphylokinase variants with engineered surface charges

  NEMERGUT Michal STULAJTEROVA Monika SKRABANA Rostislav HOVAN Andrej AMBRO L'ubos STRUNGA Alan PROKOP Zbyněk DAMBORSKÝ Jiří TOMKOVA Maria SEDLAK Erik

  Peer-reviewed scientific article

  Protein Science, year: 2026, volume: 35, edition: 3, DOI

• Early-onset hereditary spastic paraplegia type 56 (SPG56): clinical-molecular correlations and functional validation of CYP2U1 variants

  ŠUSTROVÁ Eva ŘÍHOVÁ Kamila POKORNÁ Petra HAVLOVA Veronika STIBOREK Marek ŠIMEK Zdeněk DAMBORSKÝ Jiří HORÁK Ondřej KOŽELKOVÁ Kateřina HLOUŠKOVÁ Eliška DEMLOVÁ Regina KUBÁTOVÁ Jana SLABÝ Ondřej SLABÁ Kateřina

  Peer-reviewed scientific article

  BMC Medical Genomics, year: 2026, volume: 19, edition: 1, DOI

• EnzymeMiner 2.0: advancing automated enzyme discovery with expansive sequence mining and smart property analysis

  ROSINSKÁ Monika SVOBODOVA Lucie BORKO Simeon LACKO Dávid PLANAS IGLESIAS Joan MARQUES Sérgio Manuel KABOUREK Petr LIU Baoyan PAILOZIAN Karen DAMBORSKÝ Jiří MAZURENKO Stanislav BEDNÁŘ David

  Peer-reviewed scientific article

  Nucleic acids research, year: 2026, volume: 54, edition: W1, DOI

• Experimentally validated deep learning control of protein aggregation

  CIMA Vojtech KUNKA Antonín PLANAS IGLESIAS Joan GRAKOVA Ekaterina HAVLÁSEK Martin SUBRAMANIAN Madhumalar BELOCH Michal MAREK Martin SLANINOVA Katerina DAMBORSKÝ Jiří PROKOP Zbyněk BEDNÁŘ David MARTINOVIC Jan

  Peer-reviewed scientific article

  Communications Chemistry, year: 2026, volume: 9, edition: 1, DOI

• FireProtDB 2.0: large-scale manually curated database of the protein stability data

  MUSIL Miloš BORKO Simeon PLANAS IGLESIAS Joan LACKO Dávid ROSINSKA Monika KABOUREK Petr MARTINS Ligia O. TATARUCH Mateusz DAMBORSKÝ Jiří MAZURENKO Stanislav BEDNÁŘ David

  Peer-reviewed scientific article

  NUCLEIC ACIDS RESEARCH, year: 2026, volume: 54, edition: D1, DOI

• Harmane inhibits hepatic cytochrome P450 enzymes in rats

  KLÁSKOVÁ Eva ZENDULKA Ondřej PEŠ Ondřej EYRILMEZ Saltuk Mustafa BEDNÁŘ David JUŘICA Jan

  Peer-reviewed scientific article

  Frontiers in Pharmacology, year: 2026, volume: 17, edition: August 2026, DOI

• Molecular trick to reverse SN2 step in a haloalkane dehalogenase

  TOUL Martin MARQUES Sérgio Manuel GAO Tadeja BERNHARDOVÁ Hana VÁVRA Ondřej NOVÁKOVÁ Veronika DAMBORSKÝ Jiří BEDNÁŘ David PROKOP Zbyněk MAREK Martin

  Peer-reviewed scientific article

  Chem Catalysis, year: 2026, volume: 6, edition: 5, DOI

• Rapid screening of staphylokinase protein variants using an unpurified cell-free expression system

  TOMKOVA Maria HOVANOVA Veronika DAMBORSKÝ Jiří SEDLAK Erik

  Peer-reviewed scientific article

  FEBS Open Bio, year: 2026, volume: 16, edition: 8, DOI

• Regioselective Sesquiterpene Hydroxylation Directed by Tunnel Remodeling in Rieske Oxygenases

  BERGER Jonathan B. MARQUES Sérgio Manuel WISSNER Julian L. SCHELLE Jona T. BEEKWILDER Jules DAMBORSKÝ Jiří HAUER Bernhard

  Peer-reviewed scientific article

  JACS Au, year: 2026, volume: 6, edition: 2, DOI