Ing. Jan Šimoník

2026

• Data-Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research

  ŠIMONÍK Jan LAPČÍK Petr BOUCHALOVÁ Pavla BOUCHAL Pavel

  Peer-reviewed scientific article

  Mass Spectrometry Reviews, year: 2026, DOI

2025

• DIA-MS identified transmembrane glycoprotein GPNMB as a candidate predictive biomarker and potentially a therapeutic target in metastatic renal cell carcinoma

  ŠIMONÍK Jan BOUCHALOVÁ Pavla LAPČÍK Petr POTĚŠIL David PODHOREC Ján JANÁČOVÁ Lucia HLOBILKOVÁ Alice JURÁSKOVÁ Kateřina POPRACH Alexandr HORA Milan FIALA Ondřej BOUCHAL Pavel

  Conference abstract

  Year: 2025, type: Conference abstract

• Integrated multiomics classification of triple negative breast cancer

  ŠIMONÍK Jan BOUCHALOVÁ Pavla LAPČÍK Petr JURÁSKOVÁ Kateřina KOVÁČOVÁ Ingrid POTĚŠIL David BYSTRÝ Vojtěch NENUTIL Rudolf HRSTKA Roman BOUCHAL Pavel

  Conference abstract

  Year: 2025, type: Conference abstract

• Integrated proteogenomic analysis identifies synuclein gamma as a key target of the mesenchymal stem-like subtype of triple negative breast cancer

  ŠIMONÍK Jan BOUCHALOVÁ Pavla LAPČÍK Petr JURÁSKOVÁ Kateřina POTĚŠIL David HOLÁNEK Miloš BYSTRÝ Vojtěch NENUTIL Rudolf HRSTKA Roman BOUCHAL Pavel

  Conference abstract

  Year: 2025, type: Conference abstract

• Proteomics-driven multi-omics classification of triple negative breast cancer

  ŠIMONÍK Jan BOUCHALOVÁ Pavla LAPČÍK Petr JURÁSKOVÁ Kateřina KOVÁČOVÁ Ingrid POTĚŠIL David JANÁČOVÁ Lucia HOLÁNEK Miloš TICHÝ Boris BYSTRÝ Vojtěch NENUTIL Rudolf HRSTKA Roman BOUCHAL Pavel

  Conference abstract

  Year: 2025, type: Conference abstract

2024

• Breast cancer subclassification based on proteomics/proteogenomics for targeted therapy

  LAPČÍK Petr ŠIMONÍK Jan BOUCHALOVÁ Pavla JURÁSKOVÁ Kateřina POTĚŠIL David JANÁČOVÁ Lucia TICHÝ Boris BYSTRÝ Vojtěch NENUTIL Rudolf HRSTKA Roman BOUCHAL Pavel

  Conference abstract

  Year: 2024, type: Conference abstract

• Proteogenomic Classification of Triple-Negative Breast Cancer for Prognosis and Targeted therapy

  ŠIMONÍK Jan BOUCHALOVÁ Pavla JURÁSKOVÁ Kateřina LAPČÍK Petr POTĚŠIL David BYSTRÝ Vojtěch NAVRÁTIL Jiří TICHÝ Boris NENUTIL Rudolf HRSTKA Roman BOUCHAL Pavel

  Conference abstract

  Year: 2024, type: Conference abstract

• Transmembrane glycoprotein GPNMB is a candidate predictive biomarker and potentially a therapeutic target in metastatic renal cell carcinoma

  ŠIMONÍK Jan BOUCHALOVÁ Pavla LAPČÍK Petr POTĚŠIL David PODHOREC Ján JANÁČOVÁ Lucia HLOBILKOVÁ Alice JURÁSKOVÁ Kateřina POPRACH Alexandr MILAN Hora ONDŘEJ Fiala BOUCHAL Pavel

  Conference abstract

  Year: 2024, type: Conference abstract

• Understanding breast cancer biology via proteomics, proteogenomics and interactomics to identify novel therapy targets

  LAPČÍK Petr ŠIMONÍK Jan BOUCHALOVÁ Pavla JURÁSKOVÁ Kateřina POTĚŠIL David JANÁČOVÁ Lucia TICHÝ Boris BYSTRÝ Vojtěch NENUTIL Rudolf HRSTKA Roman BOUCHAL Pavel

  Conference abstract

  Year: 2024, type: Conference abstract

2023

• Next generation proteomics identifies a potential protein marker of poor response to tyrosine kinase inhibitors in metastatic renal cell carcinoma

  BOUCHALOVÁ Pavla ŠIMONÍK Jan LAPČÍK Petr JANÁČOVÁ Lucia POTĚŠIL David PODHOREC Ján HLOBILKOVÁ Alice POPOVICI Vlad HORA Milan POPRACH Alexandr FIALA Ondřej BOUCHAL Pavel

  Conference abstract

  Year: 2023, type: Conference abstract