Mgr. Helena Peschelová, Ph.D.

2020

• CD20 is dispensable for B-cell receptor signaling but is required for proper actin polymerization, adhesion and migration of malignant B cells

  KOZLOVÁ Veronika LEDEREROVÁ Aneta LADUNGOVÁ Adriana PESCHELOVÁ Helena JANOVSKÁ Pavlína SLUSARCZYK A. DOMAGALA J. KOPČIL Pavel VAKULOVÁ Viera OPPELT Jan BRYJA Vítězslav DOUBEK Michael MAYER Jiří POSPÍŠILOVÁ Šárka ŠMÍDA Michal

  Peer-reviewed scientific article

  Plos one, year: 2020, volume: 15, edition: 3, DOI

• Combination of epigenetic drug screen and CRISPR knockout screen revealed involvement of aurora kinases and Cullin 3 in CD20 regulation

  LEDEREROVÁ Aneta KOZLOVÁ Veronika MANČÍKOVÁ Veronika PESCHELOVÁ Helena PERSSON J. SCHMIERER B. DOUBEK Michael MAYER Jiří POSPÍŠILOVÁ Šárka ŠMÍDA Michal

  Conference abstract

  Year: 2020, type: Conference abstract

• Genome-wide CRISPR/Cas9 screening reveals novel target genes, whose inactivation is able to upregulate surface expression of immunotherapy target CD20

  PESCHELOVÁ Helena DOSTÁLOVÁ Lenka KOZLOVÁ Veronika LEDEREROVÁ Aneta HEJRET Václav ŠMÍDA Michal

  Conference abstract

  Year: 2020, type: Conference abstract

• Performance of anti-CD19 chimeric antigen receptor T cells in genetically defined classes of chronic lymphocytic leukemia

  MANČÍKOVÁ Veronika PESCHELOVÁ Helena KOZLOVÁ Veronika LEDEREROVÁ Aneta LADUNGOVÁ Adriana VERNER Jan LOJA Tomáš FOLBER František MAYER Jiří POSPÍŠILOVÁ Šárka ŠMÍDA Michal

  Peer-reviewed scientific article

  Journal for ImmunoTherapy of Cancer, year: 2020, volume: 8, edition: 1, DOI

2019

• CRISPR/Cas9 gene editing and functional screening in chronic lymphocytic leukemia

  PESCHELOVÁ Helena KOZLOVÁ Veronika HEJRET Václav ŠMÍDA Michal

  Conference abstract

  Year: 2019, type: Conference abstract

• Performance of α-CD19 Chimeric Antigen Receptor T cells in genetically defined classes of Chronic Lymphocytic Leukemia

  MANČÍKOVÁ Veronika KOZLOVÁ Veronika PESCHELOVÁ Helena MAYER Jiří POSPÍŠILOVÁ Šárka ŠMÍDA Michal

  Conference abstract

  Year: 2019, type: Conference abstract

• The use of CRISPR/Cas9 technology in the study of chronic lymphocytic leukemia

  PESCHELOVÁ Helena KOZLOVÁ Veronika HEJRET Václav ŠMÍDA Michal

  Conference abstract

  Year: 2019, type: Conference abstract

2018

• CRISPR/Cas9-mediated gene knockout of TP53 and ATM in HG3 cell line: models for chronic lymphocytic leukemia

  PESCHELOVÁ Helena KOZLOVÁ Veronika POSPÍŠILOVÁ Šárka ŠMÍDA Michal

  Conference abstract

  Year: 2018, type: Conference abstract

2016

• Genomewide profiling of copy-number alteration in monoclonal gammopathy of undetermined significance

  MIKULÁŠOVÁ Aneta SMETANA Jan WAYHELOVÁ Markéta JANYŠKOVÁ Helena SANDECKÁ Viera KUFOVÁ Zuzana ALMÁŠI Martina JARKOVSKÝ Jiří GREGORA Evzen KESSLER Petr WROBEL Marek WALKER Brian WARDELL Christopher MORGAN Gareth HÁJEK Roman KUGLÍK Petr

  Peer-reviewed scientific article

  European Journal of Haematology, year: 2016, volume: 97, edition: 6, DOI

• Whole genome amplification effect on segmental copy-number changes and copy-number neutral loss of heterozygosity analysis by oligonucleotide-array based comparative genomic hybridization in human myeloma cell line

  MIKULÁŠOVÁ Aneta SMETANA Jan WAYHELOVÁ Markéta JANYŠKOVÁ Helena OKUBOTE Samuel Adeyinka HÁJEK Roman KUGLÍK Petr

  Peer-reviewed scientific article

  International Journal of Clinical and Experimental Pathology, year: 2016, volume: 9, edition: 7