Mgr. Martin Havlásek

2025

• Decoding Protein Stabilization: Impact on Aggregation, Solubility, and Unfolding Mechanisms

  HAVLÁSEK Martin MARQUES Sérgio Manuel SZOTKOWSKÁ Veronika KUNKA Antonín BABKOVÁ Petra DAMBORSKÝ Jiří PROKOP Zbyněk BEDNÁŘ David

  Article in Periodical

  Journal of Chemical Information and Modeling, year: 2025, volume: 65, edition: 16, DOI

• Modulation of Amyloid-β Aggregation by Surface Proteins from Pathogens Associated with Alzheimer's Disease

  KUNKA Antonín HŘÍBKOVÁ Hana VÁŇOVÁ Tereza POSPÍŠILOVÁ Veronika HAVLÁSEK Martin HAVIERNIK Jan RŮŽEK Daniel DAMBORSKÝ Jiří BOHAČIAKOVÁ Dáša PROKOP Zbyněk

  Article in Periodical

  ACS Chemical Neuroscience, year: 2025, volume: 16, edition: 18, DOI

2024

• AggreProt: a web server for predicting and engineering aggregation prone regions in proteins

  PLANAS IGLESIAS Joan BORKO Simeon SWIATKOWSKI Jan ELIAS Matej HAVLÁSEK Martin SALAMON Ondrej GRAKOVA Ekaterina KUNKA Antonín MARTINOVIC Tomas DAMBORSKÝ Jiří MARTINOVIC Jan BEDNÁŘ David

  Article in Periodical

  Nucleic Acids Research, year: 2024, volume: 52, edition: W1, DOI

• Upravená dehalogenáza LinB116 se zlepšenou termostabilitou

  HAVLÁSEK Martin DAMBORSKÝ Jiří BEDNÁŘ David

  Outcomes put into operation (prototype, working sample)

  Year: 2024

2023

• Advancing Enzyme's Stability and Catalytic Efficiency through Synergy of Force-Field Calculations, Evolutionary Analysis, and Machine Learning

  KUNKA Antonín MARQUES Sérgio Manuel HAVLÁSEK Martin VAŠINA Michal VELÁTOVÁ Nikola CENGELOVÁ Lucia KOVÁŘ David DAMBORSKÝ Jiří MAREK Martin BEDNÁŘ David PROKOP Zbyněk

  Article in Periodical

  ACS Catalysis, year: 2023, volume: 13, edition: 19, DOI

2021

• Computational Enzyme Stabilization Can Affect Folding Energy Landscapes and Lead to Catalytically Enhanced Domain-Swapped Dimers

  MARKOVÁ Klára KUNKA Antonín CHMELOVÁ Klaudia HAVLÁSEK Martin BABKOVÁ Petra MARQUES Sérgio Manuel VAŠINA Michal PLANAS IGLESIAS Joan CHALOUPKOVÁ Radka BEDNÁŘ David PROKOP Zbyněk DAMBORSKÝ Jiří MAREK Martin

  Article in Periodical

  ACS Catalysis, year: 2021, volume: 11, edition: 21, DOI