Ing. RNDr. Martin Marek, Ph.D., MBA

2024

• Identification of new endocrine disruptive transthyretin ligands in polluted waters using pull-down assay coupled to non-target mass spectrometry

  MIKUŠOVÁ Petra TOUŠOVÁ Zuzana SEHNAL Luděk KUTA Jan GRABICOVA K. FEDOROVA G. MAREK Martin GRABIC R. HILSCHEROVÁ Klára

  Article in Periodical

  Journal of Hazardous Materials, year: 2024, volume: 471, edition: June 2024, DOI

2023

• Advancing Enzyme's Stability and Catalytic Efficiency through Synergy of Force-Field Calculations, Evolutionary Analysis, and Machine Learning

  KUNKA Antonín MARQUES Sérgio Manuel HAVLÁSEK Martin VAŠINA Michal VELÁTOVÁ Nikola CENGELOVÁ Lucia KOVÁŘ David DAMBORSKÝ Jiří MAREK Martin BEDNÁŘ David PROKOP Zbyněk

  Article in Periodical

  ACS Catalysis, year: 2023, volume: 13, edition: 19, DOI

• Atypical homodimerization revealed by the structure of the (S)-enantioselective haloalkane dehalogenase DmmarA from Mycobacterium marinum

  ŠNAJDAROVÁ Karolína MARQUES Sérgio Manuel DAMBORSKÝ Jiří BEDNÁŘ David MAREK Martin

  Article in Periodical

  Acta Crystallographica Section D: Structural Biology, year: 2023, volume: 79, edition: November, DOI

• Catalytic mechanism for Renilla-type luciferases

  SMITH Andrea TOUL Martin PLUSKAL Daniel BAATALLAH Racha GAGNOT Glwadys RANGEL PAMPLONA PIZARRO PINTO José Gaspar SANTANA Vinicius T. T. STUCHLÁ Markéta NEUGEBAUER Petr CHAIYEN Pimchai DAMBORSKÝ Jiří BEDNÁŘ David JANIN Yves L. L. PROKOP Zbyněk MAREK Martin

  Article in Periodical

  Nature Catalysis, year: 2023, volume: 6, edition: 1, DOI

• Deciphering Enzyme Mechanisms with Engineered Ancestors and Substrate Analogues

  GAO Tadeja DAMBORSKÝ Jiří JANIN Yves L. MAREK Martin

  Article in Periodical

  ChemCatChem, year: 2023, volume: 15, edition: 19, DOI

• Domino-like effect of C112R mutation on ApoE4 aggregation and its reduction by Alzheimer’s Disease drug candidate

  NEMERGUT Michal MARQUES Sérgio Manuel UHRÍK Lukáš VÁŇOVÁ Tereza NEZVEDOVÁ Markéta GADARA Darshak Chandulal JHA Durga TULIS Jan NOVÁKOVÁ Veronika PLANAS IGLESIAS Joan KUNKA Antonín LEGRAND Anthony Thomas P HŘÍBKOVÁ Hana POSPÍŠILOVÁ Veronika SEDMÍK Jiří RAŠKA Jan PROKOP Zbyněk DAMBORSKÝ Jiří BOHAČIAKOVÁ Dáša SPÁČIL Zdeněk HERNYCHOVÁ Lenka BEDNÁŘ David MAREK Martin

  Article in Periodical

  Molecular Neurodegeneration, year: 2023, volume: 18, edition: 1, DOI

• Illuminating the mechanism and allosteric behavior of NanoLuc luciferase

  NEMERGUT Michal PLUSKAL Daniel HORÁČKOVÁ Jana ŠUSTROVÁ Tereza TULIS Jan BÁRTA Tomáš BAATALLAH Racha GAGNOT Glwadys NOVÁKOVÁ Veronika MAJEROVÁ Marika SEDLÁČKOVÁ Karolina MARQUES Sérgio Manuel TOUL Martin DAMBORSKÝ Jiří PROKOP Zbyněk BEDNÁŘ David JANIN Yves L. MAREK Martin

  Article in Periodical

  Nature Communications, year: 2023, volume: 14, edition: 1, DOI

• In cellulo and in vivo assays for compound testing against Trypanosoma cruzi

  GUERRA-SLOMPO Eloise Pavao PICCHI-CONSTANTE Gisele Fernanda Assine MAREK Martin ROMIER Christophe SIPPL Wolfgang ZANCHIN Nilson Ivo Tonin

  Article in Periodical

  STAR Protocols, year: 2023, volume: 4, edition: 1, DOI

• Multimeric structure of a subfamily III haloalkane dehalogenase-like enzyme solved by combination of cryo-EM and x-ray crystallography

  CHMELOVÁ Klaudia GAO Tadeja POLÁK Martin SMITH Andrea CROLL Tristan I. SHAIKH Tanvir ŠKAŘUPOVÁ Jana CHALOUPKOVÁ Radka DIEDERICHS Kay READ Randy J. DAMBORSKÝ Jiří NOVÁČEK Jiří MAREK Martin

  Article in Periodical

  Protein Science, year: 2023, volume: 32, edition: 10, DOI

• Study of Protein Conformational Dynamics Using Hydrogen/Deuterium Exchange Mass Spectrometry

  UHRIK Lukas HENEK Tomas PLANAS IGLESIAS Joan KUCERA Josef DAMBORSKÝ Jiří MAREK Martin HERNYCHOVA Lenka

  Chapter of a book

  Advanced Methods in Structural Biology, year: 2023, number of pages: 26 s.