Field of study: Biomolecular Chemistry
Topics of doctoral theses (supervisor)
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Recruitment of transcriptional elongation factor Spt6 to C-terminal domain of RNA polymerase II –
graduate 2019
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The Role of RNA Polymerase II CTD Mimicry in Transcription Termination in Yeast –
graduate 2019
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Structural studies of regulatory protein domains involved in eukaryotic transcription –
graduate 2017
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Structural studies of molecular machines involved in gene expression –
graduate 2013
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Transcription termination of nonpolyadenylated transcripts –
graduate 2013
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Functional and structural study of RNA-binding proteins involved in RNA metabolism –
graduate 2013
Topics of doctoral theses (consultant)
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Study of protein-RNA complexes by computational methods –
graduate 2013
Field of study: Biomolecular chemistry and bioinformatics
Topics of doctoral theses (supervisor)
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Strukturně řízený návrh a funkční validace inhibitorů proteinů Argonaute –
ongoing study
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Restoring antiviral properties of mammalian Dicer –
ongoing study
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Structural basis of miRNA processing in mammals –
graduate 2025
Field of study: Life Sciences
Topics of doctoral theses (supervisor)
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Deciphering the Argonaute Loading Mechanisms in RNA-Silencing –
ongoing study
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Deciphering the Argonaute Loading Mechanisms in RNA-Silencing Pathways –
ongoing study
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Structural and functional characterization of the interaction between RNA polymerase II and the BRCA1-BARD1 complex –
graduate 2025
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The RNA Polymerase II C-terminal domain: Condensation and interaction hub in transcription –
graduate 2025
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Structural study of torpedo termination complexes –
graduate 2025
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Structural and mechanistic studies of transcription elongation factor SPT6 –
graduate 2022
Detailed information on doctoral topics and students
