Mgr. Lukáš Maier, Ph.D.

2024

• Novel casein kinase 1 alpha inhibitors for the treatment of resistant AML and solid tumors

  JANOVSKÁ Pavlína RADASZKIEWICZ Tomasz Witold PROCHAZKOVA P PRIŠTICOVÁ Ingrid PLEŠINGEROVÁ Hana ČULEN Martin ŠMÍDA Michal BUŠA Daniel LADUNGOVÁ Adriana MAIER Lukáš HAVEL Štěpán MAYER Jiří SCHEER A PARUCH Kamil BRYJA Vítězslav

  Conference abstract

  Year: 2024, type: Conference abstract

• Unexpectedly Regioselective Diels-Alder Reactions of New Unsymmetrical Benzoquinones: A Convenient Synthetic Entry to Uniquely Substituted Decalins

  MAIER Lukáš NĚMEČKOVÁ Dana AKAVARAM Naresh KALLA Erik SEMRÁD Hugo MATYASKOVÁ Olivie MUNZAROVÁ Markéta DAĎOVÁ Petra KUBALA Lukáš ŠVENDA Jakub PARUCH Kamil

  Article in Periodical

  Chemistry - A European Journal, year: 2024, volume: 30, edition: 55, DOI

2023

• Discovery of Potent and Exquisitely Selective Inhibitors of Kinase CK1 with Tunable Isoform Selectivity

  NĚMEC Václav KHIRSARIYA PrashantKumar JANOVSKÁ Pavlína MARTÍN MOYANO Paula MAIER Lukáš PROCHÁZKOVÁ Petra KEBKOVÁ Pavlína GYBEĽ Tomáš BERGER Benedict-Tilman CHAIKUAD Apirat REINECKE Maria KUSTER Bernhard KNAPP Stefan BRYJA Vítězslav PARUCH Kamil

  Article in Periodical

  Angewandte Chemie International Edition, year: 2023, volume: 62, edition: 11, DOI

2022

• Comparing the efficiency of six clearing methods in developing seeds of Arabidopsis thaliana

  ATTULURI Venkata Pardha S. SANCHEZ LOPEZ Juan Francisco MAIER Lukáš PARUCH Kamil ROBERT BOISIVON Helene

  Article in Periodical

  Plant Reproduction, year: 2022, volume: 35, edition: 4, DOI

• Synthesis and Profiling of Highly Selective Inhibitors of Methyltransferase DOT1L Based on Carbocyclic C-Nucleosides

  KHIRSARIYA PrashantKumar POSPÍŠIL Patrik MAIER Lukáš BOUDNÝ Miroslav BABÁŠ Martin KROUTIL Ondřej MRÁZ Marek VÁCHA Robert PARUCH Kamil

  Article in Periodical

  Journal of Medicinal Chemistry, year: 2022, volume: 65, edition: 7, DOI

2021

• Highly selective inhibitors of protein kinases CLK and HIPK with the furo[3,2-b]pyridine core

  NĚMEC Václav MAIER Lukáš BERGER Benedict-Tilman CHAIKUAD Apirat DRÁPELA Stanislav SOUČEK Karel KNAPP Stefan PARUCH Kamil

  Article in Periodical

  European Journal of Medicinal Chemistry, year: 2021, volume: 215, edition: April, DOI

2019

• Furo[3,2-b]pyridine: A Privileged Scaffold for Highly Selective Kinase Inhibitors and Effective Modulators of the Hedgehog Pathway

  NĚMEC Václav HYLSOVÁ Michaela MAIER Lukáš FLEGEL Jana SIEVERS Sonja ZIEGLER Slava SCHRÖDER Martin BERGER Benedict-Tilman CHAIKUAD Apirat VALČÍKOVÁ Barbora ULDRIJAN Stjepan DRÁPELA Stanislav SOUČEK Karel WALDMANN Hebert KNAPP Stefan PARUCH Kamil

  Article in Periodical

  Angewandte Chemie International Edition, year: 2019, volume: 58, edition: 4, DOI

2017

• A Concise Synthesis of Forskolin

  HYLSE Ondřej MAIER Lukáš KUČERA Roman PEREČKO Tomáš SVOBODOVÁ Aneta KUBALA Lukáš PARUCH Kamil ŠVENDA Jakub

  Article in Periodical

  Angewandte Chemie International Edition, year: 2017, volume: 2017, edition: 56, DOI

• Diastereoselective Flexible Synthesis of Carbocyclic C Nucleosides

  MAIER Lukáš KHIRSARIYA PrashantKumar HYLSE Ondřej ADLA Santosh Kumar ČERNOVÁ Lenka POLJAK Michal KRAJČOVIČOVÁ Soňa WEIS Erik DRÁPELA Stanislav SOUČEK Karel PARUCH Kamil

  Article in Periodical

  The Journal of Organic Chemistry, year: 2017, volume: 82, edition: 7, DOI

2015

• Synthesis of carbocyclic analogs of dehydroaltenusin: identification of a stable inhibitor of calf DNA polymerase a

  KOVÁČOVÁ Silvia ADLA Santosh Kumar MAIER Lukáš BABIAK Michal MIZUSHINA Yoshiyuki PARUCH Kamil

  Article in Periodical

  Tetrahedron, year: 2015, volume: 71, edition: 40, DOI