Mgr. Hana Paculová, Ph.D.

2020

• Hypoxia/Hif1 Alpha prevents premature neuronal differentiation of neural stem cells through the activation of Hes1

  VEČEŘA Josef PROCHÁZKOVÁ Jiřina ŠUMBEROVÁ Veronika PÁNSKÁ Veronika PACULOVÁ Hana KOHUTKOVÁ LÁNOVÁ Martina MAŠEK Jan BOHAČIAKOVÁ Dáša ANDERSSON Emma Rachel PACHERNÍK Jiří

  Peer-reviewed scientific article

  Stem Cell Research, year: 2020, volume: 45, edition: May 2020, DOI

2017

• BRCA1 or CDK12 loss sensitizes cells to CHK1 inhibitors

  PACULOVÁ Hana KRAMARA Juraj ŠIMEČKOVÁ Šárka FEDR Radek SOUČEK Karel HYLSE Ondřej PARUCH Kamil SVOBODA Marek MISTRÍK Martin KOHOUTEK Jiří

  Peer-reviewed scientific article

  Tumor Biology, year: 2017, volume: 2017, edition: October, DOI

2015

• Ovarian carcinoma CDK12 mutations misregulate expression of DNA repair genes via deficient formation and function of the Cdk12/CycK complex.

  EKUMI Kingsley M. PACULOVÁ Hana LENASI Tina POSPÍCHALOVÁ Vendula BOESKEN Christian A. RYBAŘÍKOVÁ Jana BRYJA Vítězslav GEYER Matthias BLAŽEK Dalibor BARBORIC Matjaz

  Peer-reviewed scientific article

  Nucleic Acids Research, year: 2015, volume: 43, edition: 5, DOI