Informace o projektu
Molekulární patogeneze alimentární infekce virem klíšťové encefalitidy.
- Kód projektu
- GA23-07160S
- Období řešení
- 1/2023 - 12/2025
- Investor / Programový rámec / typ projektu
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Grantová agentura ČR
- Standardní projekty
- Fakulta / Pracoviště MU
- Přírodovědecká fakulta
- Spolupracující organizace
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Biologické centrum AV ČR, v. v. i.
- Odpovědná osoba RNDr. Jiří Salát, Ph.D.
Here, we propose a new 3-year research project to investigate several critical aspects of the pathogenesis of alimentary TBE. The cellular and molecular factors underlying TBEV intestinal infection, pathology, inflammatory changes, and factors involved in the TBEV infection via the digestive tract are currently poorly understood. It is critical to understand the mechanisms involved in the development and physiopathology of this largely neglected TBEV mode of infection. We will use an innovative combination of the most advanced experimental approaches and state-of-the-art in vitro and in vivo models to investigate this important, but poorly understood aspect of TBE.
Publikace
Počet publikací: 2
2024
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A brief tale of two pioneering moments: Europe's first discovery of Tick-Borne Encephalitis (TBE) virus beyond the Soviet Union and the largest alimentary TBE outbreak in history
Ticks and Tick-borne Diseases, rok: 2024, ročník: 15, vydání: 3, DOI
2023
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Editorial for the Special Issue: "Tick-Borne Encephalitis"
Microorganisms, rok: 2023, ročník: 11, vydání: 4, DOI